IRAK-4 protein kinase inhibitor 2
CAS No. 301675-24-1
IRAK-4 protein kinase inhibitor 2( —— )
Catalog No. M28816 CAS No. 301675-24-1
IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 35 | Get Quote |
|
| 25MG | 56 | Get Quote |
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| 50MG | 82 | Get Quote |
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| 100MG | 120 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameIRAK-4 protein kinase inhibitor 2
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NoteResearch use only, not for human use.
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Brief DescriptionIRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).
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DescriptionIRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).(In Vitro):IRAK-4 protein kinase inhibitor 2 inhibited IRAK-1 (IC50 <10 μM) as well.
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In VitroIRAK-4 protein kinase inhibitor 2 (compound 1) also inhibits IRAK-1, with an IC50 of <10 μM.
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetIRAK
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Recptorα1-adrenoceptor
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Research Area——
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Indication——
Chemical Information
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CAS Number301675-24-1
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Formula Weight282.259
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Molecular FormulaC14H10N4O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 10 mg/mL (35.43 mM)
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SMILES[O-][N+](=O)c1cccc(c1)C(=O)Nc1nc2ccccc2[nH]1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Boschi D, et al. New potential uroselective NO-donor alpha1-antagonists. J Med Chem. 2003 Aug 14;46(17):3762-5.
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